|
Symbol Name ID |
Sftpc
surfactant associated protein C MGI:109517 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Misalignment of the pulmonary veins |
Pulmonary arterial hypertension |
Acute infectious pneumonia |
Recurrent pneumonia |
Asthma |
Hypoxemia |
Crackles |
Bronchoconstriction |
Apnea |
Dyspnea |
Exertional dyspnea |
Respiratory distress |
Tachypnea |
Absent bronchoalveolar dimeric surfactant-protein B |
Absent bronchoalveolar surfactant-protein C |
Intraalveolar phospholipid accumulation |
Spontaneous pneumothorax |
Type II pneumocyte hyperplasia |
Desquamative interstitial pneumonitis |
Honeycomb lung |
Interstitial pneumonitis |
Nonspecific interstitial pneumonia |
Pulmonary fibrosis |
Crazy paving pattern |
Cystic pattern on pulmonary HRCT |
Nodular pattern on pulmonary HRCT |
Interlobular septal thickening |
Intralobular septal thickening |
Reticular pattern on pulmonary HRCT |
Usual interstitial pneumonia |
Emphysema |
Paraseptal emphysema |
Chronic bronchitis |
Ground-glass opacification |
Bronchial wall thickening |
Bronchiectasis |
Decreased DLCO |
Reduced forced expiratory volume in one second |
Reduced forced vital capacity |
Restrictive ventilatory defect |
Airway hyperresponsiveness |
Chronic pulmonary obstruction |
Cough |
Respiratory insufficiency |
Neonatal respiratory distress |
Respiratory failure |
Respiratory failure requiring assisted ventilation |
| Disease(s) Associated with SFTPC | |||||||||||||||||||||||||||||||||||||||||||||||
| asthma | |||||||||||||||||||||||||||||||||||||||||||||||
| chronic obstructive pulmonary disease | |||||||||||||||||||||||||||||||||||||||||||||||
| pulmonary alveolar proteinosis | |||||||||||||||||||||||||||||||||||||||||||||||
| pulmonary emphysema |
| Mouse Phenotypes | respiratory system phenotype |
abnormal lung vasculature morphology |
abnormal lung morphology |
abnormal bronchus epithelium morphology |
abnormal pulmonary alveolus epithelial cell morphology |
increased alveolar lamellar body number |
increased type II pneumocyte number |
abnormal lung interstitium morphology |
abnormal pulmonary alveolus morphology |
overexpanded pulmonary alveolus |
abnormal pulmonary interalveolar septum morphology |
emphysema |
abnormal pulmonary elastic fiber morphology |
abnormal lung hysteresivity |
increased airway resistance |
abnormal surfactant physiology |
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| Availability | Mouse Genotype | ||||||||||||||||
| Sftpctm1Swg/Sftpctm1Swg | * | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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